Staff Profile Skip to main content
Staff Profile

Dr Kar-Chun Tan

Senior Research Fellow
Office of the Provost
Faculty of Science and Engineering
Bentley Campus
+61 8 9266 9916

Brief Summary

Group leader of the 'septoria nodorum blotch biology' programme.

Back to top

Memberships, Awards and Training

2014            Eureka Prize finalist - Department of Agriculture Landcare Eureka Prize for Sustainable Agriculture.

2005            Semifinalist of the Western Australian Young Achiever Award for the Science and Technology category.

2003            Recipient of the Australian Postgraduate Award.

2002            Runner-up placing in the Western Australian division of the AusBiotech Excellence Awarded for top Honours thesis.

2002            Vice Chancellor's Commendation for Academic Excellence 2001 Award (Murdoch Univ.).

Back to top

Research Interests

  • Identification of necrotrophic effectors in Parastagonospora nodorum.
  • Signalling regulation of effector gene expression.
  • Identification of effector sensitivity/SNB QTLs in wheat.
  • Metabolomic dissection of the wheat defensome.

Back to top

Specialty Areas

  • Molecular plant pathology
  • Proteomics
  • Metabolomics
  • Genetic mapping of wheat

Back to top

Additional Information

Other Information


Dinglasan, E. G., Godwin, I. D., Phan, H. T. T., Tan, K. C., Platz, G. J. and Hickey L. T. (2018). Vavilov wheat accessions provide useful sources of resistance to tan spot (syn. yellow spot) of wheat. Plant Pathol. DOI: 10.1111/ppa.12822.

Tan, K. C. and Oliver R. P. (2017). Regulation of proteinaceous effector expression in phytopathogenic fungi. PLoS Pathog. DOI: 10.1371/journal.ppat.1006241.

Casey, T. M., Khan, J. M., Bringans, S. D., Koudelka, T., Takle, P. S., Downs, R. A., Livk, A., Syme, R. A., Tan, K. C. and Lipscombe, R. J. (2017). Analysis of reproducibility of proteome coverage and quantitation using isobaric mass tags (iTRAQ and TMT). J. Proteome Res. DOI: 10.1021/acs.jproteome.5b01154.

Rybak, K., See, P. T., Phan, H. T., Syme, R. A., Moffat, C. S., Oliver, R. P. and Tan K. C. (2017). A functionally conserved Zn2Cys6 binuclear cluster transcription factor class regulates necrotrophic effector gene expression and host-specific virulence of two major Pleosporales fungal pathogens of wheat. Mol. Plant Pathol. DOI: 10.1111/mpp.12511.

Phan, H. T. T., Rybak, K., Breen, S., Furuki, E., Solomon, P. S., Oliver, R. P. and Tan, K. C. (2016). Differential effector gene expression underpins epistasis in a plant fungal disease. Plant J. 87: 343-354. DOI: 10.1111/tpj.13203.

John, E., Lopez-Ruiz, F., Rybak, K., Mousley, C. J., Oliver, R. P. and Tan, K. C. (2016). Dissecting the role of histidine kinase and Hog1 mitogen-activated protein kinase signalling in stress tolerance and pathogenicity of Parastagonospora nodorum on wheat. Microbiol. 162: 1023-1036. DOI: 10.1099/mic.0.000280

Syme, R. A.*, Tan, K. C.*, Hane, J. K.*, Dodhia, K., Stoll, T., Hastie, M., Furuki, E., Ellwood, S. R., Williams, A. H., Tan, Y. F., Testa, A. C., Gorman, N. J. and Oliver, R. P. (2016). Comprehensive annotation of the Parastagonospora nodorum reference genome using next-generation genomics, transcriptomics and proteogenomics. PLoS One 11: e0147221. DOI:10.1371/journal.pone.0147221 *Equal contribution.

Oliver, R. P., Tan, K. C. and Moffat, C. S. (2016). Necrotrophic pathogens of wheat. In Encyclopedia of Food Grains. 2nd ed. Volume 4. Academic Press, Cambridge: 273-278.

Cockram, J., Scuderi, A., Barber, T., Furuki, E., Gardner, K. A., Rose, G. A., Gosman, N., Tan, K. C., Phan, H. P., Oliver, R. P. and Mackay, I. (2015). Fine-mapping the wheat Snn1 locus conferring sensitivity to the Parastagonospora nodorum necrotrophic effector SnTox1 using an eight founder multi-parent advanced generation intercross population. G3 5: 2257-2266.

Tan, K. C., Phan, H. T. T., Rybak, K., John, E., Chooi, Y. H., Solomon, P. S. and Oliver, R. P. (2015). Functional redundancy of necrotrophic effectors - consequences for exploitation for breeding. Frontiers Plant Sci. 6: 501 DOI:10.3389/fpls.2015.00501.

Tucker, M. A., Moffat, C. S., Ellwood, S. R., Tan, K. C., Jayasena, K. and Oliver R. P. (2014). Development of genetic SSR markers in Blumeria graminis f. sp. hordei and application to isolates from Western Australia. Plant Pathol. 64: 337-343. DOI: 10.1111/ppa.12258.

Tan, K. C., Waters, O. D. C., Rybak, K., Antoni, E., Furuki, E. and Oliver, R. P. (2014). Sensitivity to three Parastagonospora nodorum necrotrophic effectors in current Australian wheat cultivars and the presence of further fungal effectors. Crop Pasture Sci. 65: 150-158.

Tan, K. C. and Oliver R. P. (2014). Metabolomics and proteomics to dissect fungal phytopathogenicity. In The Mycota XIII. Springer-Verlag, Berlin: 301-314. (invited manuscript)

Oliver, R., Lichtenzveig, J., Tan, K. C., Waters, O., Rybak, K., Lawrence, J., Friesen, T. and Burgess, P. (2014). No yield penalty associated with insensitivity to necrotrophic effectors. Plant Pathol. 63: 1027-1035. DOI: 10.1111/ppa.12191.

Tan, K. C., Ferguson-Hunt, M., Rybak, K. Waters, O. D. C., Stanley, W., Bond, C., Stuckenbrock, E. H., Friesen, T. L., Faris, J. D., McDonald, B. A. and Oliver, R. P. (2012). Quantitative variation in effector activity of ToxA haplotypes in Stagonospora nodorum and Pyrenophora tritici-repentis. Mol. Plant-Microbe Interact. 25: 515-522.

Vincent, D., Tan, K. C., Cassidy, L., Solomon, P. S. and Oliver, R. P. (2012). Plant fungal pathogens proteomic techniques. In Methods in Molecular Biology. Springer-Verlag, Berlin: 835: 75-96.

Tan, K. C., Oliver, R. P., Solomon, P. S. and Moffat, C. (2010). Proteinaceous necrotrophic effectors in fungal virulence. Func. Plant Biol. 37: 907-912 (corresponding author and issue frontcover image).

IpCho, S. V. S., Tan, K. C., Koh, G., Gummer, J., Oliver, R. P., Trengove, R. D. and Solomon, P. S. (2010). The Transcription Factor StuA regulates central carbon metabolism, mycotoxin production and host-specific toxin expression in the wheat pathogen Stagonospora nodorum. Eukaryot. Cell 9: 1100-1108.

Casey, T., Solomon, P. S., Bringans, S., Tan, K. C., Oliver, R. P. and Lipscombe, R. L. (2010). Quantitative proteomic analysis of G-protein signalling in Stagonospora nodorum using Isobaric Tags for Relative and Absolute Quantification (iTRAQ). Proteomics, 10: 1-10.

Tan, K. C., IpCho, S. V. S., Trengove, R. D., Oliver, R. P. and Solomon, P. S. (2009). Assessing the impact of transcriptomics, proteomics and metabolomics on fungal phytopathogenicity. Mol. Plant Pathol. 10: 703-715.

Bringans, S., Hane, J. K., Casey, T., Tan, K. C., Lipscombe, R. J., Solomon, P. S. and Oliver, R. P. (2009). Deep proteogenomics; high throughput gene validation by multidimensional liquid chromatography and mass spectrometry of proteins from the fungal wheat pathogen Stagonospora nodorum. BMC Bioinformatics 10: 301-309.

Tan, K. C., Trengove, R. D., Maker, G. L., Oliver, R. P. and Solomon, P. S. (2009). Metabolite profiling identifies the mycotoxin alternariol in the pathogen Stagonospora nodorum. Metabolomics 5: 330-335.

Liu Z., Faris, J. D. Oliver, R. P., Tan, K. C., Solomon, P. S. McDonald, M. C., McDonald, B. A., Nunez, A., Rasmussen, J. B. and Friessen, T. L. (2009). SnTox3 acts in effector triggered susceptibility to induce disease on wheat carrying the Snn3 Gene. PLoS Pathogens 5:e1000581.

Tan, K. C., Heazlewood, J. L. Millar, A. H., Oliver, R. P. and Solomon, P. S. (2009). Proteomic identification of Ga signalling-regulated targets in the phytopathogenic fungus Stagonospora nodorum. Mycol. Res. 113: 523-531.

Solomon, P. S., IpCho, S. V. S.,  Hane, J. K.,  Tan, K. C. and Oliver, R. P. (2008). A quantitative PCR approach to determine gene copy number. Fungal Genet. Rep. 55: 5-8.

Tan, K. C., Thomson, G., Millar, A. H., Oliver, R. P. and Solomon, P. S. (2008). A signaling-regulated, short-chain dehydrogenase of Stagonospora nodorum regulates asexual development. Eukaryot. Cell 7: 1916-1929 (Issue front cover image).

Hane, J. K., Lowe, R. G. T., Solomon, P. S.,  Tan, K. C., Schoch, C. L., Spatafora, J. W., Crous, P. W., Kodira, C., Birren, B. W., Torriani, S. F. F., McDonald, B. A. and Oliver, R. P. (2007). Dothideomycete-plant interaction illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum. Plant Cell 19: 3347-3368.

Solomon, P. S., Lowe, R. G. T., Tan, K. C., Waters, O. D. C. and Oliver, R. P. (2006). Stagonospora nodorum: cause of stagonospora nodorum blotch of wheat. Mol. Plant Pathol. 7: 147-156.

Ding, J. L., Tan, K. C, Thangamani, S., Kusuma, N., Seow, W. K., Bui, T. H. N., Wang, J. and Ho, B. (2005). Spatial and temporal coordination of expression of immune response genes during Pseudomonas infection of horseshoe crab, Carcinoscorpius rotundicauda. Genes Immun. 6: 557-574.

Solomon, P. S., Tan, K. C. and Oliver, R. P. (2005). Mannitol-1-phosphate metabolism is required for sporulation in planta of the wheat pathogen Stagonospora nodorum. Mol. Plant-Microbe Interact. 18: 110-115.

Solomon, P. S., Tan, K. C., Sanchez, P., Cooper, R. M. and Oliver, R. P. (2004). The disruption of a Ga subunit sheds new light on the pathogenicity of Stagonospora nodorum on wheat. Mol. Plant-Microbe Interact. 17: 456-466.

Solomon, P. S., Tan, K. C. and Oliver, R. P. (2003). The nutrient supply of pathogenic fungi; a fertile field for study.  Mol. Plant Pathol. 4: 203-210.

Research grant

Millar, A. H., Clode, P. L., Flematti, G. R., Leedman, P. J., Zhang, Dongke, Grice, K., Bunce, M., Oliver, R. P., Tan, K. C., Trengove, R. D., Maker, G. L., Thompson, R. C., Wilton, S. D., Martins, R. N., Abbiss, C. R., Boyce, M. C. High resolution mass spectrometry for metabolomics and proteomics research. ARC LIEF LE150100158. 2015 - AUD$670,000.

Tan, K. C. Septoria nodorum blotch of wheat. GRDC-Curtin University bilateral. 2014-2019. AUD$5,758,258

Sampson, D. D, Koutsantonis, G. A., Johns, M. L., Zhang, D., Swaminatha-Iyer, K. L., Trengove, R. D., Oliver, R. P., Ogden, M. I., Verdile, G., Abbiss, C. R., Tan, K. C. and Godfrey, I. M. Nuclear magnetic resonance spectroscopy facilities: advancing cutting-edge chemical, biological, energy and materials research. ARC LIEF LE140100036. 2014 – AUD$771,000.

Tan, K. C. Early Career Researcher Highest Research Performance Index. Research and Development RPI Awards 2012 – AUD$3,000.

Grice, K., Oliver, R. P., Charrois, J. W., Greenwood, P. F., Linge, K. L., Flematti, G. L., Tan, K. C. and Dodson, J. R. Automated preparative gas chromatograph for isolating unique and important organic components for structural identification. ARC LIEF LE120100077. 2012 - AUD$150,000.

Back to top